How to get Active workbook instance

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Hi i am trying to build an app in python to open the excel files. We can get this done using Dispatch / DispatchEX. But, as per my requirement, i need to open the file in an excel window which was selected by the user. In short, the excel file has to be opened in the Active workbook. I tried "win32com.client.GetActiveObject("Excel.Application")", but it doesnt work. Any suggestions please
 

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